NoteSuppression of Tea and of Lipopolysaccharide - induced Liver Injury Coffee in D - Galactosamine - sensitized Rats JSgeA by Various Types

cinogenic, antibiotic, antihypercholesterolemic, antihyperglycemic, antihypertensive, and antiinflammatory actions. In addition, we have demonstrated that green tea and such constituents as fiavonol glycosides, theanine and soluble dietary fiber had a protective effect against D-galactosamine (GalN)-induced liver injury in rats,3'6) We have also found that lipopolysaccharide (LPS)-induced liver inj ury, one of the most frequently applied liver injury models, was effectively suppressed by green tea in GalN-sensitized rats, and that this effect of green tea could mainly be attributable to caffeine (unpublished results). The latter finding suggests the possibility that cafieinecontaining beverages might generally protect animals from LPS-induced liver injury, and that the potency of the effect of a beverage might be dependent on the